Start Submission Become a Reviewer

Reading: Risk factors for acquiring varicella zoster virus (VZV) infection, and sero-prevalence of an...

Download

A- A+
dyslexia friendly

Research Articles

Risk factors for acquiring varicella zoster virus (VZV) infection, and sero-prevalence of anti-VZV immunoglobulin G antibodies in adolescents from a tropical population

Authors:

F Noordeen ,

Faculty of Medicine, University of Peradeniya, LK
About F

Senior Lecturer

Department of Microbiology, Faculty of Medicine               University of Peradeniya,                                               Peradeniya, Sri Lanka.

 

X close

R Dissanayake,

Department of Microbiology, Faculty of Medicine, University of Peradeniya, LK
X close

IKB Weerasekara,

Department of Microbiology, Faculty of Medicine, University of Peradeniya, LK
About IKB
Department of Microbiology, Faculty of Medicine,
University of Peradeniya, Sri Lanka
X close

PVR Kumarasiri,

Department of Community Medicine, Faculty of Medicine, University of Peradeniya, LK
About PVR

Department of Community Medicine, Faculty of Medicine,

University of Peradeniya, Sri Lanka

X close

MH Wijedasa

Department of Microbiology, Faculty of Medicine, University of Peradeniya, LK
About MH

Department of Microbiology, Faculty of Medicine,

University of Peradeniya, Sri Lanka

X close

Abstract

Introduction: Little is known about the sero-prevalence of anti-VZV antibodies among adolescents in the Kandy district of Sri Lanka although adulthood VZV infections are very common in this part of the country.

Design: Socio-demographic data and blood samples were collected between November 2004 and April 2005 from a total of 271, 12- to 19-year-old, school students from urban, rural and estate communities. Sera were tested for anti-VZV IgG antibodies using a stranded enzyme-linked immunosorbent assay.

Results: Sero-prevalence of anti-VZV antibodies among the adolescents was found to be 34%. Number of siblings (adolescents without siblings were non-immune; of those with 2 siblings - 27% were immune; of those with more than 2 siblings - 39% were immune) and areas of residence (urban, estate and rural) were significantly associated with the presence of anti-VZV IgG antibodies (p<0.001).

Conclusions: Sero-prevalence of anti-VZV IgG antibodies was low among adolescents in the Kandy district. Adolescents who lived in the urban areas had a significantly higher rate of anti-VZV IgG antibodies than those who lived in rural areas (p<0.001). Adolescents who grow up without siblings are at risk of evading the childhood VZV infection and form a potential target group for adulthood chicken pox.

DOI: http://dx.doi.org/10.4038/sljid.v4i1.5852

 

How to Cite: Noordeen, F. et al., (2014). Risk factors for acquiring varicella zoster virus (VZV) infection, and sero-prevalence of anti-VZV immunoglobulin G antibodies in adolescents from a tropical population. Sri Lankan Journal of Infectious Diseases. 4(1), pp.30–37. DOI: http://doi.org/10.4038/sljid.v4i1.5852
Published on 25 Feb 2014.
Peer Reviewed

Downloads

  • PDF (EN)

    comments powered by Disqus